structured population model

Tuesday, May 29, 2018 - 2:00pm - 2:50pm
Suzanne Sindi (University of California, Merced)
Prion proteins cause a variety of fatal neurodegenerative diseases in mammals but are harmless to yeast, making it an ideal model organism for these diseases. My research focuses on stochastic and deterministic models of both prion protein dynamics within individual yeast cells as well as how those yeast cells grow and divide to create a heterogeneous colony of cells. Determining kinetic parameters of prion replication in yeast are complicated because experiments reflect both the disease and yeast population dynamics.
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