Migraine is a prevailing disease in present day population. Cortical spreading depression (CSD) - a depolarisation wave that originates in the visual region and propagates across the cortex to the peripheral areas - has been deemed, by several studies, a correlate of visual aura, a neurological phenomenon preceding migraine and causing perceptual disturbance. As of today, little is known about the mechanisms that can trigger or stop such phenomenon. However, the complex and highly individual characteristics of the brain cortex suggest that the
