cell volume

Monday, March 12, 2018 - 2:00pm - 2:50pm
Sean Sun (Johns Hopkins University)
Cell volume regulation is fundamentally important in phenomena such as cell growth, proliferation, tissue homeostasis and embryogenesis. How the cell size is set, maintained, and changed over a cell's lifetime is not well understood. In this work we focus on how the volume of non-excitable tissue cells is coupled to the cell membrane electrical potential and the concentration of membrane-permeable ions in the cell environment.
Wednesday, February 14, 2018 - 1:30pm - 2:30pm
Yina Wei (University of California, San Diego)
The brain consumes 20% of the body’s metabolic energy with muscles and digestive system at rest, despite being only 2% of the human body mass. The majority of the brain’s metabolic energy is dedicated to restoring ionic gradients due to neuronal activities. The delicate balance between metabolic energy supply and expenditure becomes critically strained in pathological activity of the brain such as seizure and spreading depression, during which requires massive rearrangement of ions across the plasma membrane.
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