Multiple Imputation

Thursday, November 8, 2018 - 5:00pm - 5:30pm
Abdus Wahed (University of Pittsburgh)
Hypothesis testing to compare dynamic treatment regimes (DTR) from a sequential multiple assignment randomization trial (SMART) is generally based on inverse probability weighting or g-estimation. However, regression methods allowing for comparison of DTRs that flexibly adjust for baseline covariates using these methods are not as straight-forward due to the fact that one patient can belong to multiple DTRs. This poses a challenge for data analysts as it violates basic assumptions of regression modeling of unique group membership.
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