Wednesday, February 14, 2018 - 10:30am - 11:30am
William Lytton (SUNY Downstate Medical Center)
Multiscale modeling has arisen as a focus of computational systems biology, with the realization that genome, proteome, connectome, etceteromes, can become comprehensible only when placed in the context of explicit computer simulations. Measurements and activity patterns at one scale must be understood dynamically in the context of patterns at higher and lower scales. Nowhere is this more apparent than in the domain of brain ischemia, where manipulations at molecular levels are used, so far unsuccessfully, to protect cells that are otherwise at risk of death.
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