Covariate-adaptive design

Thursday, September 14, 2017 - 3:30pm - 4:00pm
Feifang Hu (George Washington University)
Precision medicine is the systematic use of information pertaining to an individual patient to select or optimize the patient’s preventative and therapeutic care. In recent literature, biomarkers have been classified to predictive biomarkers and prognostic biomarkers based one their role in clinical studies. To design a clinical trial for precision medicine, one should include both predictive and prognostic biomarkers. In this talk, we will propose a new family of covariate-adjusted response-adaptive designs, which incorporate these biomarkers as well as the responses.
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