The Topology of Fragile X

Thursday, December 12, 2013 - 3:15pm - 4:05pm
Keller 3-180
David Romano (Stanford University)
Fragile X syndrome (FXS), due to mutations of the FMR1 gene, is the most common known inherited cause of developmental disability as well as the most common single-gene risk factor for autism. In this talk I will give a brief description of the algorithm used by Mapper/Iris to produce a Reeb-like graph representation associated to a dataset, and then describe how its application to structural MRI data for a population of children with FXS has led to the potential identification of higher and lower functioning subgroups within this population.