Modeling Electrodiffusion and Osmosis in Physiological Systems

Friday, July 26, 2013 - 8:40am - 9:30am
Keller 3-180
Yoichiro Mori (University of Minnesota, Twin Cities)
Electrolyte and cell volume regulation is essential in physiological systems.
After a brief introduction to cell volume control and electrophysiology,
I will discuss the classical pump-leak model of electrolyte and cell volume control.
I will then generalize this to a PDE model that allows for the
modeling of tissue-level electrodiffusive and osmotic phenomena.
This model will then be applied to the study of cortical spreading depression,
a pathophysiological phenomenon in the brain that is thought to underlie
migraine aura and other pathologies.
MSC Code: