Uniquely biological challenges for rheology

Thursday, September 17, 2009 - 1:15pm - 2:00pm
EE/CS 3-180
M. Gregory Forest (University of North Carolina, Chapel Hill)
The goal of this lecture is to inform the audience of the types of challenges that arise, and open problems that remain, in a specific class of biological fluids: mucus. Mucus is prevalent in biology and its rheology is fundamental for: locomotion (e.g., of snails); flow transport (e.g., of mucosal layers in mammalian lungs); and controlling diffusive transport of invasive particles (e.g., in the nasal cavity, lung, and reproductive organs). Mucus varies dramatically across species, across populations, across organs, and in a single organ across disease states. The lecture will address challenges faced in the Virtual Lung Project at UNC for design of experiments, for data-based inference of constitutive parameters, and for development of direct simulation tools for lung biology and medical applications.
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