Multiscale structural mechanics of viruses: Stretching<br/><br/>the limits of continuum modeling<br/><br/><br/><br/>

Monday, November 3, 2008 - 9:15am - 10:00am
EE/CS 3-180
William Klug (University of California, Los Angeles)
The last several years have seen a number of successful applications of continuum elasticity theory to the study of virus mechanics. Continuum modeling has been particularly effective in connection with atomic force microscopy nanoindentation experiment for understanding and predicting material properties of viral shells (capsids), and may hold promise for illuminating the physics of capsid assembly as well. I will consider the question of the limitations of continuum modeling of capsids, and discuss some examples of how conventional continuum theory is being extended or stretched to study multiscale features linked to the inherently discrete character of these molecular assemblies.
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