On Problems in DNA Elasticity in Which Electrostatic Forces, the Sequence Dependence of Elastic Properties and the Impenetrability of the DNA Molecule Must<br/><br/>all be Taken into Account

Sunday, September 16, 2007 - 5:15pm - 5:30pm
EE/CS 3-180
Bernard Coleman (Rutgers, The State University of New Jersey)
In this talk on DNA elasticity, that is based on recent
research of Yoav Biton and is an extension of earlier research
of Biton, Coleman, and Swigon, it will be shown that there are
cases in which self-contact occurs even though the
intramolecular electrostatic forces of repulsion are strong.
The theory to be presented permits one to calculate minimum
energy configurations of supercoiled non-homogeneous DNA
minicircles and the dependence on linking number and salt
concentration of the proximity and relative orientation of
sequentially remote sites whose interaction can be a matter of
biological importance.

Y.Y. Biton, B.D. Coleman, D. Swigon, On bifurcations of
intrinsically curved, electrically charged, rod-like structures
that model DNA molecules in solution,
J. Elasticity 87, 187-210, 2007.