DNA Mechanics: Deformation and Recognition

Sunday, September 16, 2007 - 9:15am - 10:15am
EE/CS 3-180
Richard Lavery (Centre National de la Recherche Scientifique (CNRS))
DNA can easily be deformed by external factors including molecular interactions and applied forces. We have
used molecular modeling and simulation to investigate the structural and energetic nature of these deformations
both in generic terms and, more finely, to understand their sequence dependence and therefore to decode their
role in recognition processes.
MSC Code: