The Analysis of Proteomics Spectra from Serum Samples
Wednesday, October 1, 2003 - 9:30am - 10:20am
Keith Baggerly (The University of Texas at Austin)
Mass spectrometry profiles can provide quick summaries of the relative levels of hundreds of proteins. By surveying profiles from a large number of samples, we can hopefully zoom in on proteins that are linked with a difference of interest such as the presence or absence of cancer. Using examples from two case studies, we will address issues of experimental design, data cleaning and processing, discriminating subsets, and protecting against spurious structure.