Poxviruses and Adaptive Genome Evolution

Wednesday, October 22, 2003 - 11:00am - 11:50am
Keller 3-180
Aoife McLysaght (Trinity College)
We used complete sequence from twenty poxviruses to investigate the evolution of these virus genomes. We examined the pattern of genome content and genome arrangement evolution in the context of the virus phylogeny. We also examined the patterns of positive selection acting on genes in these genomes. We show that the rate of genome evolution is not constant over time, and that it may be possible to relate patterns of genome evolution and adaptive evolution acting on genes.