The Landscape of Comparative Genomics in Mammals
Tuesday, October 21, 2003 - 1:30pm - 2:20pm
Stephen O'Brien (National Cancer Institute)
Dense genetic maps of human, mouse and rat genomes that are based on coding genes, microsatellite and single nucleotide polymorphism (SNP) markers have been complemented by precise gene homologue alignment with moderate resolution maps of livestock, companion animals and additional mammal species. Comparative genetic assessment expands the utility of these maps in gene discovery, in functional genomics, and in tracking the evolutionary forces that sculptured the genome organization of modern mammalian species.