Comparative Gene Prediction

Monday, October 20, 2003 - 1:30pm - 2:20pm
Keller 3-180
Roderic Guigó (Instituto Municipal de Investigación Mèdica (IMIM))
Comparative genomics is emerging as a powerful tool to characterize complex genomes. Gene prediction, in particular, has benefited from the availability of genome sequences from organisms across the whole eukaryotic spectrum. The comparison of the human and mouse genome sequences, for instance, has contributed substantially to refine the gene content of the human (and mouse) genomes. In my talk, I will stress how comparative genomes may be particularly useful to identify genes which deviated from the standard characteristics, and that, for this reason, may escape identification by other means.