ImmSim: A Cellular Automaton Model for Simulation of the Immune System

Tuesday, October 13, 1998 - 2:00pm - 2:30pm
Keller 3-180
Phillip Seiden (IBM)
We have constructed a model for simulating the immune system with the idea of using it as a vehicle for performing experiments in machina, experiments in the computer. The model is based on a cellular automaton which allows relatively easy inclusion of many of the complexities of real immunological systems, often allows the parameters and interactions of the model entities to be entered in a transparently biological manner, and quite naturally exhibits the variation and fluctuations encountered in in vivo and in vitro experiments. The original humoral model has been extended to include new function and a new model including both the cellular and humoral systems has been developed. I will discuss the capabilities of the present models, present some results that have been obtained, and describe some of the work being undertaken with the new extensions.