Exploitation of Chromosomal Locations to Establish Functions of Genes

Sunday, April 25, 1999 - 2:15pm - 3:00pm
Keller 3-180
Ross Overbeek (Argonne National Laboratory)
Recently, we developed a technique for predicting that a pair of genes have related functions. The technique exploits the tendency for genes to cluster with related genes (we argue that this occurs over 1/3 of the time) and depends on the existence of a fairly large number of genomes. Since the number of available genomes has risen considerably, we are now able to discuss a number of specific conjectures relating to genes in E.coli. My talk will summarize the technique and present a number of results relating to the E.coli genes.