Introduction
Proteomics is critical to our understanding of cellular
biological processes
Mass Spectrometry (MS) has emerged as a key platform
in proteomics for the high-throughput identification of
proteins
Sophisticated algorithms, such as Mascot or Sequest,
exist for database searching of MS/MS data
Major bottleneck: results must often be manually validated
More robust algorithms are needed before the
identification of MS/MS data can be fully automated