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Proteomics
is critical to our understanding of cellular
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biological
processes
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Mass
Spectrometry (MS) has emerged as a key platform
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in
proteomics for the high-throughput identification of
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proteins
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Sophisticated
algorithms, such as Mascot or Sequest,
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exist
for database searching of MS/MS data
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Major
bottleneck: results must often be manually validated
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More
robust algorithms are needed before the
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identification
of MS/MS data can be fully automated
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