Talk Abstract:
Direct Treatment of Uncertainties in Complex Models and Decision
Making
Gregory
J. McRae
Department of Chemical Engineering
Massachusetts Institute of Technology
Cambridge, MA 02139
mcrae@mit.edu
and
Cheng Wang
Reaction Design
6440 Lusk Boulevard, Suite D-209
San Diego, CA 92121
chengw@ReactionDesign.com
Mathematical models are core technologies for improving production
efficiency, lowering operating costs and reducing environmental
impacts of modern manufacturing processes. While more powerful
computers have enabled additional details to be incorporated
into individual models a more serious problem has emerged. What
is now limiting how fast a solution can be obtained is not the
computer capability but the time needed to build and analyze
the models themselves. Indeed, one of the inevitable consequences
of using models is that approximations and uncertainties are
involved. The issue is not that there are uncertainties, they
are always present, the real challenge is to identify those
inputs that have the most influence on the predictions. This
information is vital for deciding how to allocate resources
for additional experiments, prototypes or building better models.
When the models are large, or when there are many parameters,
even the best Monte Carlo, or importance based sampling methods
for uncertainty analysis can be prohibitively expensive. One
consequence is that systematic uncertainty analyses are often
never carried out. This presentation will describe a set of
practical tools for performing systematic uncertainty analysis
of complex models and their use in decision making. The methodology
is based on a new computational efficient method for uncertainty
analysis called the Deterministically Equivalent Modeling Method
(DEMM) that is based on transforming the stochastic model into
an equivalent deterministic form. A key output from the algorithm
is the probability distribution of the output responses given
the descriptions of the uncertain input parameters. The method
is two to four orders of magnitude faster than traditional Monte
Carlo methods and it can also determine the contributions of
individual parameters to the variance in the model predictions.
The seminar will also describe how the uncertainty analysis
methods can be used to develop model-based approaches to experimental
design, hypothesis testing and decision making.
Material used during the talk
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to Workshop Schedule
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to Decision Making under Uncertainty: Assessment of the Reliability
of Mathematical Models
1999-2000
Reactive Flow and Transport Phenomena
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