HOME    »    PROGRAMS/ACTIVITIES    »    Annual Thematic Program
Talk Abstract
Mechanisms of Synaptic Enhancement and Depression

Institute for Mathematics and Its Applications
Arthur Sherman, NIH

Mechanisms at the terminal level for synaptic enhancement on several time-scales (facilitation, augmentation, post-tetanic potentiation) and depression will be discussed. Issues to be considered will include the roles of residual free Ca2+ and residual Ca2+ bound to ``memory proteins", and the roles of domain and macroscopic Ca2+. We will also explore to what extent synaptic depression can be accounted for in terms of vesicle depletion and resupply.

Back to Workshop Schedule