Ben-Gurion University of the Negev
The primary function of cilia is the transportation of either
a single cell through water or materials over the cellular tissue
surface. For this task to be performed efficiently, cilia beat
in approximately periodic, spatial and temporal pattern called
the metachronal wave. Ciliary cells are excitable, in the sense
that they dramatically change their activity in response to
various stimuli. The characterization of ciliary activity, i.e.
frequency, metachronal wavelength and its direction, under normal
and stimulated conditions will be presented. In addition, the
underlying molecular events leading to ciliary activation induced
by extracellular ATP will be discussed.