Recently, we developed a technique for predicting that a pair of genes have related functions. The technique exploits the tendency for genes to cluster with related genes (we argue that this occurs over 1/3 of the time) and depends on the existence of a fairly large number of genomes. Since the number of available genomes has risen considerably, we are now able to discuss a number of specific conjectures relating to genes in E.coli. My talk will summarize the technique and present a number of results relating to the E.coli genes.

Back to IMA "HOT TOPICS" Workshop: Challenges and Opportunities in Genomics: Production, Storage, Mining and Use

1998-1999 Mathematics in Biology

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