I will develop and analyze mathematical models for two different topics. For the first topic I will use an epidemic control model to assess the problems of how to use moderately effective vaccines to control the HIV epidemic in the gay community in San Francisco. Specifically, I will analyze the impact on vaccine effectiveness of the interaction of mechanism of failure and changes in risk behavior. For, the second topic I will use mathematical models to address the problem of how to design effective HIV epidemic control strategies when more than one subtype of HIV is present.

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1998-1999 Mathematics in Biology