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Partially supported by the National Institute of General Medical Sciences,National Institutes of Health (NIHNIGMS)
Organizers:
Philip
Maini
Universtiy of Oxford
James
D. Murray
University of Washington
and
Hans
Othmer
University of Utah
Pattern formation and morphogenesis in developmental biology involves the spatiotemporal coordination of growth, cellcell signaling, tissue movement, gene expression and cell determination. The spatial pattern of signals to which cells respond may be set up by diffusion, or it may consist of local modifications to the extracellular matrix that cells detect and respond to. The cellular response to these signals can involve oriented cell movement (chemotaxis), signal relay, and gene activation, while cellular movement can in turn alter the mechanical stresses in a tissue, thereby enhancing or retarding movement. This workshop will focus on the fundamental aspects of chemotaxis, cell and tissue movement, and chemical and mechanical mechanisms for pattern formation. Applications of these basic processes in the context of specific developmental systems will be the focus of the second workshop.
This workshop will bring together leading theoreticians from the mathematical and biological communities. The mathematical problems to be discussed include pattern formation in reactiondiffusion systems (how are patterns generated reliably in the face of biological variation), the longterm behavior of chemotaxis equations (are there stable, bounded nonconstant solutions or do solutions blow up in finite time), and issues of effective homogenization (how does one incorporate information about the microscopic behavior of individual cells into a macroscopic continuum description). Computational aspects that arise include effective methods for computing solutions of systems of reaction diffusion (RD) equations or coupled RD/fluid problems in three space dimensions, and the numerical bifurcation analysis of systems of partial differential equations.
All talks are in Lecture Hall EE/CS 3180 unless otherwise noted.
Tuesday  Wednesday  Thursday  Friday 
TUESDAY, SEPTEMBER 8  

8:45 am  Registration and Coffee  Reception Room EE/CS 3176  
9:15 am  W.
Miller, F. Dulles, H. Othmer 
Introduction and Overview  
9:30 am  Alex
Mogilner, Univ. of CaliforniaDavis 
Five Steps Of Cellular Crawling: Many Questions, Few Answers  
10:30 am  Break  Reception Room EE/CS 3176  
11:00 am  Micah
Dembo,
Boston University 
The Stress Field at the CellSubstrate Interface in Motile Cells  
1:30 pm  Dean
Bottino, University of Utah 
ReactionDiffusion Equations And Mechanochemical Coupling On Irregular Deforming Domains  
2:30 pm  Break  Reception Room EE/CS 3176  
2:45 pm  Robert
Tranquillo, University of Minnesota 

4:00 pm  IMA Tea  400 Lind Hall  
WEDNESDAY, SEPTEMBER 9  
9:15 am  Coffee Break  Reception Room EE/CS 3176  
9:30 am  Roseanne
Ford,
University of Virginia 
MacroscopicLevel Parameters For Bacterial Motility And Chemotaxis Derived From Cell Balance Equations Which Incorporate MicroscopicLevel Swimming Behavior  
10:30 am  Break  Reception Room EE/CS 3176  
11:00 am  Angela
Stevens,
Universität Heidelberg 
ChemotaxisEquations and Approximating Models  
2:00 pm  WeiMing
Ni,
University of Minnesota 
SpikeLayer Steady States in Diffusion Systems  
3:00 pm  Break  Reception Room EE/CS 3176  
3:30 pm  Michel
Rascle, University of Nice 
Finite Time Aggregation In Some Models Of Chemotaxis  
THURSDAY, SEPTEMBER 10  
8:45 am  Coffee Break  Reception Room EE/CS 3176  
9:00 am  Cornelis
Weijer,
University of Dundee 
Control of Coordinated Cell Movement during Morphogenesis: Experiments And Models  
10:00 am  Thomas
Hoefer, Humboldt University Berlin 
An Analytical Model Of The Chemotactic Instability During Dictyostelium Aggregation  
11:00 am  Break  Reception Room EE/CS 3176  
11:15 am  David
Knecht, University of Connecticut 
Motility Of Dictyostelium Amoebae During Morphogenesis  
POSTER, VIDEO AND SOFTWARE DEMONSTRATION in Lind Hall Rooms 400, 407 and 409  
2:00 pm 
Nick F. Britton, University of Bath 
Poster: Stochastic Simulation of Tumour Growth Using the Potts Model  
Edmund J. Crampin, University of Oxford 
Poster: Pattern Sequences from ReactionDiffusion on Growing Domains  
Roseanne Ford, University of Virginia 
Poster: Mathematical Model for Integrating the Chemotactic Response of E. Coli Bacteria to Competing Signals from an Attractant and a Repellant  
Thomas
Hillen,
University of Utah 
Poster: Hyperbolic Models For Chemotaxis 

Jaap
Kaandorp, University of Amsterdam 
Poster: Modeling Growth and Form of Marine Sessile Organisms and the Impact of Hydrodynamics 

Atsushi Mochizuki, Kyushu University 
Poster: Estimating Cell Lineage From Distributions of Randomly Introduced Markers 

6:00 pm  Workshop Dinner  Vincent
Hall Room 120
Thai food buffet from Sawatdee Restaurant 

FRIDAY, SEPTEMBER 11  
9:10 am  Coffee Break  Reception Room EE/CS 3176  
9:30 am  Jonathan
A. Sherratt,
University of Warwick 
Signal Range and Spatial Patterns in Juxtacrine Signalling  
10:30 am  Coffee Break  Reception Room EE/CS 3176  
11:00 am  Nick
Monk,
University of Sheffield 
Linking Patterning And Planar Polarity In Epithelia  
2:003:00 pm  Round Table Discussion  Open to all workshop participants and is not strictly limited to the hour scheduled 
Tuesday  Wednesday  Thursday  Friday 
Name

Affiliation

Department

Daniel Bentil  University of Massachusetts  Dept. of Mathematics & Statistics 
Dean Bottino  University of Utah  Dept. of Mathematics 
Nicholas Britton  University of Bath  School of Mathematics 
Edmund Crampin  Oxford University  Centre for Mathematical Biology 
John Dallon  HeriotWatt University  Dept. of Mathematics 
Micah Dembo  Boston University  Dept. of Biomedical Engineering 
Robert Dillon  Tulane University  Dept. of Mathematics 
Roseanne M. Ford  University of Virginia  Dept. of Chemical Engineering 
Eamonn Gaffney  Centre for Mathematical Biology  Mathematical Institute 
Thomas Hillen  University of Utah  Dept. of Mathematics 
Thomas Hoefer  Humboldt University Berlin  Theoretical Biolphysics, Institute of Biology 
Jaap Kaandorp  University of Amsterdam  Parallel Scientific Computing & Simulation Group 
David Knecht  University of Connecticut  Dept. of Biological Sciences 
Howard Levine  Iowa State University  Dept. of Mathematics 
Philip Maini  University of Oxford  Math Institute 
Daphne Manoussaki  NIH/NIDCD/LCB  Dept. of Applied Mathematics 
Hans Meinhardt  MaxPlanck Institut fuer Entwicklungsbiologie  
Masayasu Mimura  Hiroshima University  Dept. of Mathematics 
Atsushi Mochizuki  Kyushu University  Dept. of Biology 
Alexander Mogilner  University of CaliforniaDavis  Dept. of Mathematics 
Nick Monk  University of Sheffield  Developmental Genetics Programme 
WeiMing Ni  University of Minnesota  School of Mathematics 
Hans G. Othmer  University of Utah  Dept. of Mathematics 
Kevin Painter  University of Utah  Dept. of Mathematics 
Eirikur Palsson  University of Utah  Dept. of Mathematics 
J. Pearson  Los Alamos National Laboratory  Applied Theoretical Physics Division 
M. Rascle  University of Nice  Laboratoire de Mathematiques 
Faustino SanchezGarduno  Cuidad Universitaria  Departamento de Matematicas 
Todd Shaw  University of Utah  Dept. of Mathematics 
Johanthan A. Sherratt  University of Warwick  Dept. of Nonlinear Systems Laboatory 
Angela Stevens  Universitaet Heideberg  Institut fuer Angewandte Mathematik 
Philippe Tracqui  UJF, Fac de Medecine  TIMCIMAG, CNRS UMR 5525 
Robert Tranquilo  University of Minnesota  Dept. of Chemical Eng. and Material Sciences 
Kees Weijer  University of Dundee  Dept. of Anatomy and Physiology 
David Wollkind  Washington State University  Dept. of Pure and Applied Mathematics 