Tuesday, May 14, 2013 - 2:00pm - 2:50pm
Timothy Elston (University of North Carolina, Chapel Hill)
Polarity establishment, the formation of a front and back, is fundamental to many cellular processes. Two examples where cell polarization plays a central role are during migration and the budding process of Saccharomyces cerevisiae (yeast). Key signaling proteins involved polarity establishment are the Rho GTPases, which act as molecular switches. We combine mathematical modeling with experimental studies to investigate the role of Rho GTPases in both budding and cell migration.
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