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IMA Tutorial

Mathematics of Nucleic Acids

September 15, 2007
Organizers:
Wilma Olson Chemistry and Chemical Biology, Rutgers University
David Swigon Mathematics, University of Pittsburgh

Schedule Participants Program Application Feedback
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Abstracts and Talk Materials Dining Guide
Workshop: Mathematics of DNA Structure, Function, and Interactions
September 16-21, 2007

Description:

This tutorial will be divided into two parts. In the first part Wilma K. Olson will start with an introduction to sequence-dependent information content in known three-dimensional structures of nucleic acids and the implications of this information on larger-scale genetic control. In the second part of the tutorial David Swigon will be present the main concepts, ideas, and results used in the research on DNA topology, elasticity and statistical mechanics. The topics will include, for example, the notion of the linking number, writhe, and twist of closed DNA, the Calugareanu-White theorem, discussions of the elastic rod model, base-pair level model, and worm-like chain model. Emphasis will be placed on the underlying principles that give rise to sequence-dependent fine structure, deformability, and recognition, and how one can use this information in low-resolution modeling of polymeric properties such as ease of spontaneous loop closure or the positioning of nucleosomes. Both lecturers will discuss experimental results that lead to the development of models and the implications of models for the understanding of the behavior of biological systems.

Schedule
Saturday | 
  Saturday, September 15
8:15a-8:45a Coffee and registration   EE/CS 3-176
8:50a-9:00a Welcome Douglas N. Arnold (University of Minnesota) EE/CS 3-180
9:00a-10:00a Sequence-dependent helical structure and global responses of DNA Part I. Wilma K. Olson (Rutgers University) EE/CS 3-180
10:00a-10:30a Break   EE/CS 3-176
10:30a-11:30a Part II: Implications of base sequence-dependent structural information on larger-scale genetic control Wilma K. Olson (Rutgers University) EE/CS 3-180
11:00a-1:30p Lunch    
1:30p-2:30p Part I: DNA topology and geometry/DNA elasticity David Swigon (University of Pittsburgh) EE/CS 3-180
2:30p-3:00p Break   EE/CS 3-176
3:00p-4:00p Part II: DNA statistical mechanics/DNA dynamics David Swigon (University of Pittsburgh) EE/CS 3-180
4:00p-4:30p Second chances Wilma K. Olson (Rutgers University), David Swigon (University of Pittsburgh) EE/CS 3-180

LIST OF CONFIRMED PARTICIPANTS

NameDepartmentAffiliation
Pranav AgarwalDepartment of Electrical Engineering University of Minnesota
Tanuj AggarwalDepartment of Electrical Engineering University of Minnesota
Ramzi AlsallaqInstitute of Molecular Biophysics Florida State University
Douglas N. ArnoldSchool of Mathematics University of Minnesota
F. Javier ArsuagaDepartment of Mathematics San Francisco State University
Nathan A. BakerDepartment of Biochemistry and Molecular Biophysics Washington University School of Medicine
Daniel J. BatesInstitute for Mathematics and its Applications University of Minnesota
John BaxterInstitute for Mathematics and its Applications University of Minnesota
Yermal Sujeet BhatInstitute for Mathematics and its Applications University of Minnesota
Victor BloomfieldDepartment of Biochemistry University of Minnesota
Richard J. BraunDepartment of Mathematical Sciences University of Delaware
Hannah CallenderInstitute for Mathematics and its Applications University of Minnesota
Larry Carson 3M
Brandon ChabaudSchool of Mathematics University of Minnesota
Shi-Jie ChenDepartment of Physics University of Missouri
Gregory S. ChirikjianDepartment of Mechanical Engineering Johns Hopkins University
Bernard D. ColemanSchool of Engineering Rutgers University
Jeremy CuruksuSchool of Engineering and Science Jacobs University
Luke CzaplaDepartment of Chemistry and Chemical Biology Rutgers University
Isabel K. DarcyDepartment of Mathematics University of Iowa
Melanie DeVriesMathematics Department University of Iowa
Marcia O. FenleyDepartment of Physics Florida State University
Efi Foufoula-GeorgiouCivil Engineering Department University of Minnesota
Andrew GastineauMathematics and Engineering Department University of Minnesota
Anant GodboleDepartment of Mathematics East Tennessee State University
Jack GoldfeatherDepartment of Mathematics and Computer Science Carleton College
Jason E. GowerInstitute for Mathematics and its Applications University of Minnesota
Christine E. HeitschSchool of Mathematics Georgia Institute of Technology
Milena HeringInstitute for Mathematics and its Applications University of Minnesota
Peter HinowInstitute for Mathematics and its Applications University of Minnesota
Tiefeng JiangDepartment of Statistics University of Minnesota
Dan JungBiomedical Engineering Department University of Minnesota
Alex KasmanDepartment of Mathematics College of Charleston
Christopher KauffmanDepartment of Computer Science University of Minnesota
Christine A KelleyDepartment of Mathematics Ohio State University
Soojeong KimDepartment of Mathematics University of Iowa
Debra KnisleyDepartment of Mathematics East Tennessee State University
Christian E. LaingDepartment of Mathematics, Chemistry New York University
Ham Ching Lam University of Minnesota
Jörg LangowskiDivision of Biophysics of Macromolecules Deutsches Krebsforschungszentrum (Cancer Research)(DKFZ)
Anton LeykinInstitute for Mathematics and its Applications University of Minnesota
Sookkyung LimDepartment of Mathematical Sciences University of Cincinnati
Chun-Chi LinDepartment of Mathematics National Taiwan Normal University
Maggie LinakCEMS University of Minnesota
Roger LuiDepartment of Mathematical Sciences Worcester Polytechnic Institute
Laura LuratiInstitute for Mathematics and its Applications University of Minnesota
Jennifer MannDepartment of Mathematics University of Texas
Kyle McQuistenDepartment of Mathematics University of Iowa
Catherine (Katy) A. MicekDepartment of Mathematics University of Minnesota
Ezra MillerSchool of Mathematics University of Minnesota
Kenneth C. MillettDepartment of Mathematics University of California, Santa Barbara
Hyeyoung MoonDepartment of Mathematics University of Iowa
David MorrisseyMathematics and Physics Department University of Minnesota
Timothy NewmanDepartment of Physics Arizona State University
Olalla Nieto FazaDepartment of Chemistry University of Minnesota
Duane NykampSchool of Mathematics University of Minnesota
Wilma K. OlsonDepartment of Chemistry and Chemical Biology Rutgers University
John OpreaDepartment of Mathematics Cleveland State University
Daniel Osei-KuffuorScientific Computation University of Minnesota
Hans G. OthmerDepartment of Mathematics University of Minnesota
Teresita Ramirez-RosasDepartment of Mathematics University of California, Santa Barbara
Huzefa RangwalaDepartment of Computer Science University of Minnesota
Dale RolfsenDepartment of Mathematics University of British Columbia
Luca RondiSchool of Mathematics University of Minnesota
George RubleinDepartment of Mathematics College of William and Mary
Murti SalapakaElectrical and Computer Engineering Department University of Minnesota
Deena SchmidtInstitute for Mathematics and its Applications University of Minnesota
Tamara Schmidt-Hegge University of Minnesota
Hullas SehcalDepartment of Electrical Engineering University of Minnesota
Chehrzad ShakibanInstitute of Mathematics and its Application University of Minnesota
Koya ShimokawaDepartment of Mathematics Saitama University
Sushmita SinghGenomics University of Minnesota
Andrzej StasiakLaboratoire d'Analyse Ultrastructurale University of Lausanne
Andrew M. SteinInstitute for Mathematics and its Applications University of Minnesota
De Witt L. SumnersDepartment of Mathematics Florida State University
Vladimir SverakSchool of Mathematics University of Minnesota
David SwigonDepartment of Mathematics University of Pittsburgh
Andrew TraversDepartment of Cell Biology MRC Laboratory of Molecular Biology
Erkan TüzelInstitute for Mathematics and its Applications University of Minnesota
Tanya VassilevskaCenter for Applied Scientific Computing Lawrence Livermore National Laboratory
Mariel VazquezDepartment of Mathematics San Francisco State University
Haiyan WangDepartment of Mathematical Sciences and Applied Computing Arizona State University
Zhian WangInstitute for Mathematics and its Applications University of Minnesota
Peng Wu Rockefeller University
Zhijun WuDepartment of Mathematics Iowa State University
Yanji Xu Minnesota Supercomputing Institute
Hongchao ZhangInstitute for Mathematics and its Applications University of Minnesota
Guohui ZhengDepartment of Chemistry and Chemical Biology Rutgers University