## Set file for C:\tyson\odefiles\WinPP\UCHSC\P10_Pancreatic_beta_cell.ode on Wed May 19 00:37:13 2004 3 Number of equations and auxiliaries 17 Number of parameters # Numerical stuff 1 nout 40 nullcline mesh 5 Gear 30000 total 1 DeltaT 0 T0 0 Transient 100 Bound 1e-012 DtMin 1 DtMax 1e-005 Tolerance 0 Max Delay 100 Eigenvector iterates 0.001 Eigenvector tolerance 0.001 Newton tolerance 0 Poincare plane 1e-005 Boundary value tolerance 1e-005 Boundary value epsilon 20 Boundary value iterates 0 Poincare None 1 Poincare variable 1 Poincare sign 0 Stop on Section 0 Delay flag 29999 Current time 29999 Last Time 2 MyStart 1 INFLAG # Delays 0.0 0.0 0.0 # Bndry conds 0 0 0 # Old ICs -37.63652881433122 V 0.08687882913723219 W 0.1261597895407973 CAI # Ending ICs -66.39593579599965 V 0.0001233723052047259 W 0.1732074444475009 CAI # Parameters 5300 C 28.6 phi -75 Vk 2700 gk 25 Vca 1000 gca -75 VL 150 gL -20 v1 24 v2 -16 v3 11.2 v4 5 Kkca 2000 gkca 0.001 rho 4.5e-006 alpha 0.18 vpump # Graphics 0.7071097251469876 rm -0.4999999999826661 rm 0.4999958366025516 rm 0.7071038372138505 rm 0.5000041633974484 rm -0.4999999999826661 rm 0 rm 0.7071038372138505 rm 0.7071097251469876 rm 0 1 2 1 0 0 1 2 1 0 0 1 2 1 0 0 1 2 1 0 0 1 2 1 0 0 1 2 1 0 0 1 2 1 0 0 1 2 1 0 0 1 2 1 0 0 1 2 1 0 -1000 1000 0 0 3DFlag 1 Timeflag 0 Colorflag 0 Type 1 color scale 0 minscale 30000 xmax 0 xmin 25 ymax -75 ymin 12 zmax -12 zmin 15000 6.666666666666667e-005 -25 0.02 0 0.08333333333333333 45 Theta 45 Phi 0 xshft 0 yshft 0 zshft 0 xlo -75 ylo 0 -1 30000 xhi 25 yhi 20 1 RHS etc ... dV/dT= (-GCA*MINF*(V-VCA)-GK*W*(V-VK)-GL*(V-VL)-IKCA)/C dW/dT= (WINF-W)/TAU dCAI/dT= RHO*(-ALPHA*GCA*MINF*(V-VCA) - VPUMP*CAI) where ... TAU = PHI/COSH((V-V3)/(2*V4)) MINF = 0.5*(1+TANH((V-V1)/V2)) WINF = 0.5*(1+TANH((V-V3)/V4)) IKCA = GKCA*CAI*(V-VK)/(KKCA+CAI)